With growing maturation of biotechnology and peptide synthesis techniques, more and more peptide drugs have been developed and applied in clinic. Peptide drugs, which have a broad range of indications and show high safety and significant efficacy, have been widely used in the prevention, diagnosis and treatment of many diseases such as cancer, hepatitis, diabetes and AIDS, possessing broad development prospects. The sources, characteristics and preparation methods of peptide drugs were briefly introduced. Especially, the research and development profiles of peptide drugs both at home and abroad, the main peptide drugs approved abroad in recent years and the main peptide drugs developed independently and entered into clinical trials in our country were reviewed in this paper.They will provide a reference for the future development of this class of new drugs. |